.500 Wyoming Express

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The .500 Wyoming Express is a handgun cartridge of the "big bore" handgun calibers. Like most handgun calibers of this size, only revolvers can fire them. It is designed mainly for hunting rather than self defense or tactical usage. The cartridge is comparable in size to the .50 Action Express, but has higher powder loads and normally a lower velocity. Though not as powerful as the .500 Smith & Wesson Magnum, the .500 Wyoming Express is one of the most powerful handgun calibers available.

Reference

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