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2C-B

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2C-B
Chemical name4-Bromo-2,5-dimethoxy-phenethylamine or
2-(4-bromo-2,5-dimethoxyphenyl)-1-aminoethane
Chemical formulaC10H14BrNO2
Molecular mass260.13 g/mol
Melting point 237 - 239 °C decomposition (hydrochloride)
215 °C (hydrobromide)
208 - 209 °C (acetate)
CAS number66142-81-2
SMILESNCCC1=C(OC)C=C(Br)C(OC)=C1
Chemical structure of 2C-B

2C-B is a lesser known psychedelic drug that was first synthesized by Alexander Shulgin in 1974. The chemical is 4-bromo-2,5-dimethoxyphenethylamine. In his book PIHKAL (Phenethylamines I Have Known and Loved), Shulgin lists the dosage range as 16–24 mg. 2C-B is a white powder sometimes found in pressed tablets or gel caps and is almost always taken orally or intranasally.

Origins and history

2C-B was synthesized from 2-5-dimethoxybenzaldehyde by Alexander Shulgin in 1974. On December 20, 1994, in a notice of proposed rulemaking published in the Federal Register (59 FR 65521) and after a review of relevant data, the Deputy Administrator of the Drug Enforcement Administration (DEA) proposed to place 4-bromo-2,5-DMPEA into Schedule I, making 2C-B illegal in the United States. This became permanent law July 2, 1995. Prior to this, 2C-B was commercially available as an aphrodisiac under the tradename "Eros" which was manufactured by the German phamaceutical company Drittewelle. Recently 2C-B has been distributed under the street name "Nexus." In the past 2C-B has also been distributed as "Eve", "Venus", "Bees", and (incorrectly) "bromo-mescaline." Internationally, 2C-B is a Schedule II drug under the Convention on Psychotropic Substances[link].

Toxicity

Not much information is known about the toxicity of 2C-B. Because 2C-B lacks an alpha-methyl group it isn't considered an amphetamine such as MDMA or methamphetamine. 2C-B does not seem to deplete the brain of serotonin, and this suggests that it may not share the neurotoxic characteristics of most amphetamines.

There are no known deaths caused by 2C-B, however it is a drug that has been used thousands of times by a broad cross-section of the populace. Few (if any) certifiable studies have been conducted on 2C-B, so its physiological and psychological characteristics are relatively unknown.

Dosage

At minor oral doses (such as 2–5 mg,) 2C-B produces an entactogenic effect, but at common recreational doses (ranging from 10–25 mg) the drug can produce intense visual and auditory effects, a thorough evaluation of the effects is farther down in the article. It is very rare that 2C-B is insufflated. [link]

By default, great care should be taken if one is recreationally experimenting with hallucinogens such as 2C-B or LSD. Notably, science has proven that many psychedelic drugs have some effect on the behavior of the mind, and such drugs may not interact well with users who have moderate-serious psychological disorders, such as schizophrenia or clinical depression.

Effects of 2C-B

The consumption of 2C-B produces the following effects.[link] Common recreational dosage is 10-25 mg.[link] As dosage increases, so does the intensity of the effects. (*)-Highly dosage dependent.

See also

External links

Categorization

Psychedelic phenethylamines [http://encycl.opentopia.com/ edit]

 


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