5-MeO-DMT

Encyclopedia : 5 : 5M : 5ME : 5-MeO-DMT

5-MeO-DMT
Chemical formula C₁₃H₁₈N₂O
Chemical name 5-Methoxy-N,N-dimethyltryptamine or
5-methoxy-3-[2-(dimethylamino)ethyl]indole
Molecular mass 218.298 g/mol
Melting point 67.7 °C (154 °F)
CAS number 1019-45-0
SMILES COC1=CC2=C(NC=C2CCN(C)C)C=C1
5-MeO-DMT is a very powerful psychedelic tryptamine. It is found in a wide variety of plant and toad species, and like its close relative DMT, it has been used as an entheogen by South American shamans for over 1200 years.

5-MeO-DMT
Chemical formula	C₁₃H₁₈N₂O
Chemical name	5-Methoxy-N,N-dimethyltryptamine or 5-methoxy-3-[2-(dimethylamino)ethyl]indole
Molecular mass	218.298 g/mol
Melting point	67.7 °C (154 °F)
CAS number	1019-45-0
SMILES	COC1=CC2=C(NC=C2CCN(C)C)C=C1

Contents

1 Chemistry
2 History
3 Use and effects
4 External links

Chemistry

5-MeO-DMT was first synthesized in 1936, and in 1959 it was isolated as one of the psychoactive ingredients of Anadenanthera peregrina seeds used in Yopo snuff.

History

Traditionally 5-MeO-DMT has been used as a psychedelic snuff, such as Yopo or Vilca, and may be a trace constituent of ayahuasca when plants such as Diplopterys cabrerana are used as an admixture. 5-MeO-DMT is also found in the venom of the Colorado River toad (Bufo alvarius), although there is no direct evidence this was used as a hallucinogen until recent times.

Use and effects

When used as a drug in its purified form, 5-MeO-DMT is smoked, snorted, or injected and is active at a dose of as little as 2mg. 5-MeO-DMT is also active orally, when taken with an monoamine oxidase inhibitor, but according to numerous reports, the combination with MAOI is extremely unpleasant and has a strong bodyload. According to the researcher Jonathan Ott, 5-MeO-DMT is active orally with doses over 30mg without aid of an MAOI.

The onset of effects occurs in seconds after smoking/injecting, or minutes after insufflating, and the experience is sometimes described as similar to a near-death experience. Peak effects last for approximately 5-10 minutes, when smoked. When insufflated, the peak effects are considerably less intense, but last for 15-25 minutes on average.

External links

Psychedelic tryptamines [http://encycl.opentopia.com/ edit]
4-Acetoxy-DET \| 4-Acetoxy-DIPT \| α-ET \| α-MT \| Baeocystin \| Bufotenin \| DET \| DIPT \| DMT \| DPT \| EIPT \| Ethocin \| Iprocin \| MET \| MIPT \|5-MeO-α-ET \| 5-MeO-α-MT \| 5-MeO-DALT \| 5-MeO-DET \| 5-MeO-DIPT \| 5-MeO-DMT \| 5-MeO-DPT \| 5-MeO-MIPT \| Miprocin \| Norbaeocystin \| Psilocin \| Psilocybin \|

Tryptamines [http://encycl.opentopia.com/ edit]
4-Acetoxy-DET > 4-Acetoxy-DIPT \| 5-MeO-α-ET \| 5-MeO-α-MT \| 5-MeO-DALT \| 5-MeO-DET \| 5-MeO-DIPT \| 5-MeO-DMT \| 5-MeO-DPT \| 5-MeO-MIPT \| α-ET \| α-MT \| Baeocystin \| Bufotenin \| DET \| DIPT \| DMT \| DPT \| EIPT \| Ethocin \| Ibogaine \| Iprocin \| MET \| MIPT \| Miprocin \| Melatonin \| NMT \| Norbaeocystin \| Psilocin \| Psilocybin \| Rizatriptan \| Serotonin \| Sumatriptan \| Tryptamine \| Tryptophan

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