5q- syndrome
Encyclopedia : 5 : 5Q : 5QS : 5q- syndrome
5q- syndrome is a rare disorder caused by loss of part of the long arm (q arm) of human chromosome 5. This syndrome affects myeloid (bone marrow) cells, causing treatment-resistant anemia, and myelodysplastic syndromes that may lead to acute myelogenous leukemia.
Lenalidomide is a new agent that is showing promise in treating 5q- syndrome.
Reference
- OMIM [153550]
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