AD-mix
Encyclopedia : A : AD : ADM : AD-mix
AD-mix is a chiral ligand and stands for the Asymmetric dihydroxylation mix. This chemical mixture is employed in the Sharpless bishydroxylation reaction. This product is commercially available comes in two variations, AD-mix α and AD-mix β.
In AD-mix α DHQ2PHAL (top) is the phthalazine adduct with dihydroquinine.
In AD-mix β; DHQD2PHAL is the phthalazine adduct with dihydroquinidine.
One mix is used for each one of the enantiomers. The mix further contains:
- Osmium catalyst potassium osmate K2OsO2(OH)4
- co-oxidant for the regeneration of osmium potassium ferricyanide K3Fe(CN)6
External links
- Catalytic Asymmetric Dihydroxylation of Alkenes at Imperial College London [Link]
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