The cranial nerve nuclei schematically represented; dorsal view. Motor nuclei in red; sensory in blue. The olfactory and optic centers are not represented. (Abducens nucleus is VI)
|- style="text-align: center;" class="hiddenStructure"
| colspan="2" |
Damage to the abducens nucleus causes monocular medial ophthalmoparesis: specifically, loss of the ability to move the ipsilateral eye outward (abduction). This is also seen in damage of the abducens nerve. In contrast, damage to the area of the nucleus can also result in lateral gaze paralysis: loss of the ability to move both eyes conjugately away from the side of the lesion. This is due to damage to both the motoneurons and interneurons projecting through the medial longitudinal fasciculus to the contralateral medial rectusneurons.