Alamethicin
Encyclopedia : A : AL : ALA : Alamethicin
Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. It contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. The peptide sequence is:
Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-Glu-Gln-Phl
(Ac = acetyl, Phl = phenylalaninol)
CAS number: 27061-78-5
In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules.
Vendors' product pages
- [Alamethicin] from Fermentek
- [Alamethicin] from AGScientific
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