Antispasmodic

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An antispasmodic is a drug that suppresses smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or bladder.

Both dicyclomine and hyoscyamine are antispasmodic due to their anticholinergic action. Both of these drugs have general side effects and can worsen gastroesophageal reflux disease [link].

Peppermint oil has been traditionally used as an antispasmodic, and a [review] of studies on the topic found that it "could be efficacious for symptom relief in IBS" (as an antispasmodic) although more carefully controlled studies are needed. A later [study] showed it is an effective antispasmodic when test-applied topically to the intestine during endoscopy.

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