Benzoylecgonine
Encyclopedia : B : BE : BEN : Benzoylecgonine
|
Ecgonine benzoate | |
| IUPAC name: 3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylic acid | |
| CAS number 519-09-5 | ATC code ? |
| Chemical formula | C16H19NO4 |
| Molecular weight | 289.326 g/mol |
| Bioavailability | ? |
| Metabolism | ? |
| Elimination half life | ? |
| Excretion | ? |
| Pregnancy category | ? |
| Legal status | DEA Schedule II |
| Delivery | ? |
Indicated for:
|
Contraindications:
|
| Side effects:
Severe:
Atypical sensations:
|
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver.
In 2005, scientists found surprisingly large quantities of Benzoylecgonine in Italy's Po River and used its concentration to estimate the number of cocaine users in the region.[link] In 2006, a similar study was performed in the Swiss ski town of Saint-Moritz using waste water to estimate the daily cocaine consumption of the population. [link]
See also
- Methylecgonine cinnamate
- Truxilline
- Hydroxytropacocaine
- Tropacocaine
- Ecgonine
- Cuscohygrine
- Dihydrocuscohygrine
- Hygrine
External links
- For a full list of external links to MSDSs, spectroscopic data, commercial chemicals suppliers etc. for this compound, see [Chemical sources].
From Wikipedia, the Free Encyclopedia. Original article here. Support Wikipedia by contributing or donating.
All text is available under the terms of the GNU Free Documentation License See Wikipedia Copyrights for details.
