Bronchodilator
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A bronchodilator is a medication intended to improve bronchial airflow. Treatment of bronchial asthma is the most common application of these drugs. They are also intended to help expand the airways and improve the breathing capacity of patients with emphysema, pneumonia and bronchitis. Pharmaceutically bronchodilators belong to β-2 mimetics - they act on β-2 receptors in bronchial smooth muscle and bronchial mucous membranes. Bronchodilators, particularly non-prescription ones, are often misused as stimulants. A common side effect of these medications is desensitization, which may produce refractory bronchospasm[.]
Bronchodilators are either short acting or long acting. Short-acting medications provide quick or "rescue" relief from acute asthma symptoms. Long-acting bronchodilators help to control and prevent symptoms. The three types of bronchodilators are beta2-agonists (short and long acting), anticholinergics (short acting), and theophylline (long acting).
Short-acting beta2-agonists These are quick-relief or "rescue" medications that provide fast, temporary relief from asthma symptoms or flare-ups. They are effective within 20 minutes or less and can last from four to six hours.These inhaled medications are best for treating sudden and severe or new asthma symptoms.Taken 15 to 20 minutes ahead of time, these medications can also prevent asthma symptoms triggered by exercise or exposure to cold air.Frequent or regular use of short-acting beta2-agonists is an indication that your asthma is not under control. Consult with your doctor to review your condition and to adjust your control medications.
Long-acting beta2-agonists These are long-term medications used to control and prevent asthma symptoms over time and are not for fast relief. They take longer to begin working, but relieve airway constriction for up to 12 hours. Inhaled - Commonly taken twice a day with an anti-inflammatory medication, they maintain open airways and prevent asthma symptoms, particularly at night. Oral - Long-acting albuterol is available in pill or syrup form. Effective for 12 hours, albuterol is particularly helpful for nighttime asthma symptoms. Because this medication requires high dosing, there tend to be increased side effects. Therefore it is not commonly prescribed. Side effects include increased heart rate, hyperactivity, feeling nervous, shaky, or over-excited, and very rarely, upset stomach or difficulty sleeping.
Anticholinergics Only available as an inhalant, ipratropium bromide relieves acute or new asthma symptoms. Because it has no effect on asthma symptoms when used alone, it is most often paired with a short-acting beta2-agonist.While it is considered a relief or rescue medication, it can take a full hour to begin working. For this reason it plays a minor role in asthma treatment. Dry throat is the most common side effect. If the medication gets in contact with the eyes, it may cause blurred vision for a brief time.
Theophylline Available in oral and injectible form, theophylline is a long-acting bronchodilator that prevents asthma episodes.It is prescribed in severe cases of asthma or those that are difficult to control. It must be taken daily and doses cannot be missed. Blood tests are required to monitor therapy and to indicate when dosage adjustment is necessary.Side effects can include nausea, vomiting, diarrhea, stomach or headache, rapid or irregular heart beat, muscle cramps, nervous or jittery feelings, and hyperactivity. These symptoms may signal the need for an adjustment in your medication.It may promote acid reflux, also known as GERD, by relaxing the lower esophageal sphincter muscle. Some medications, such as seizure and ulcer medications and antibiotics containing erythromycin, can interfere with the way theopylline works. Coffee, tea, colas, cigarette smoking, and viral illnesses can all affect the action of theopylline and change it effectiveness. Communicate any change related to these factors to your doctor so that the dose can be altered to fit the new conditions
Brand names of common bronchodilators :
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