Cardiac markers

Encyclopedia : C : CA : CAR : Cardiac markers

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Medical tests that are often referred to as cardiac markers include:

• cardiac troponin (the most sensitive and specific test for myocardial damage)
• creatine kinase (CK, also known as phosphocreatine kinase or creatine phosphokinase)
• Aspartate transaminase (AST, also called Glutamic Oxaloacetic Transaminase (GOT/SGOT) or aspartate aminotransferase (ASAT))
• lactate dehydrogenase (LDH)
• Myoglobin (Mb) has low specificify for myocardial infarction and is used less than the other markers.

Cardiac markers are substances released from heart muscle when it is damaged as a result of myocardial infarction. Depending on the marker, it can take between 2 to 24 hours for the level to increase in the blood. Additionally, determining the levels of cardiac markers in the laboratory - like many other lab measurements - takes substantial time. Cardiac markers are therefore not useful in diagnosing a myocardial infarction in the acute phase. The clinical presentation and results from an ECG are more appropriate in the acute situation.

See also

• Myocardial markers in myocardial infarction

External links

• [Quick overview, with graph]
• [eMedicine -- more detailed]

 

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