Cefalexin
Encyclopedia : C : CE : CEF : Cefalexin
Cefalexin (INN) (IPA: [kɛfəˈlɛksən, sɛfə-]) or cephalexin (USAN) is a first-generation cephalosporin antibiotic. It is an orally-administered agent with a similar antimicrobial spectrum to the intravenous agents cefalotin and cefazolin. It is commonly marketed under the trade name Keflex (Lilly).
Clinical use
- Main article: Cephalosporin
Indications
Cefalexin is used to treat urinary tract infections, respiratory tract infections (including sinusitis, otitis media, pharyngitis, tonsillitis and pneumonia), skin and soft tissue infections.Although it is not generally considered first-line therapy for any indication, it is a useful alternative to penicillins in patients with penicillin hypersensitivity. There is, however, cross-reactivity in 10% of patients with hypersensitivity to penicillins and carbapenems.
Formulations
Cefalexin is commonly marketed as capsules (250 mg and 500 mg), tablets, and powder for oral suspension (125 mg/5 mL and 250 mg/5 mL).It is marketed by generic pharmaceutical manufacturers under a wide range of brand names, including: Apo-Cephalex, Biocef, Cefanox, Ceporex, Cilex, Keflet, Keflex, Keforal, Keftab, Keftal, Lopilexin, and Panixine Disperdose.
See also
| Cephalosporin Antibiotics (J01D) [http://encycl.opentopia.com/ edit] |
|---|
| J01DB First Generation: |
| J01DC Second Generation: |
| J01DD Third Generation: |
| J01DE Fourth Generation: |
External links
- [MedlinePlus Drug Information: Cephalosporins (systemic)] – information from USP DI Advice for the Patient
- [FDA Drug Information PDF] and Pharmacy Drug Information Insert.
From Wikipedia, the Free Encyclopedia. Original article here. Support Wikipedia by contributing or donating.
All text is available under the terms of the GNU Free Documentation License See Wikipedia Copyrights for details.