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Corynebacterium

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Corynebacterium is a genus of Gram-positive, facultatively anaerobic, non-motile actinobacteria. Most do not cause disease, but are part of normal human skin flora.

Some nondiphtheria species of Corynebacterium produce disease in specific animal species, and some of these are also human pathogens. Some species attack healthy hosts, and others attack immunosuppressed hosts. Some of their effects include granulomatous lymphadenitis, pneumonitis, pharyngitis, skin infections, and endocarditis. Endocarditis caused by Corynebacterium spp. is particularly seen in patients with indwelling intravascular devices.

Infection by diphtheroids tend to occur in elderly, neutropenic, or immunocompromised patients, and those who have indwelling prosthetic devices such as heart valves, neurologic shunts, or catheters.

Certain Corynebacterium species are used in the industrial production of amino acids such as lysine.

Species

Corynebacterium diphtheriae

Nondiphtheriae Corynebacteria (diphtheroids)

References

 


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