Entrez
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The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. NCBI is part of the National Library of Medicine (NLM), itself a department of the National Institutes of Health (NIH) of the United States government.
Searching
Entrez is a powerful federated search engine, or web portal that allows users to search a multiple of discrete health sciences databases, maintained by the National Center for Biotechnology Information with a single query string and user interface. NCBI includes the following databases:
- PubMed: biomedical literature citations and abstracts, including Medline - articles from (mainly medical) journals, often including abstracts. Links to PubMed Central and other full-text resources are provided to articles from the 1990s.
- PubMed Central: free, full text journal articles
- Site Search: NCBI web and FTP web sites
- Books: online books
- OMIM: online Mendelian Inheritance in Man
- OMIA: online Mendelian Inheritance in Animals
- Nucleotide: sequence database (GenBank)
- Protein: sequence database
- Genome: whole genome sequences and Mapping
- Structure: three-dimensional macromolecular structures
- Taxonomy: organisms in GenBank Taxonomy
- SNP: single nucleotide polymorphism
- Gene: gene-centered information
- HomoloGene: eukaryotic homology groups
- PubChem Compound: unique small molecule chemical structures
- PubChem Substance: deposited chemical substance records
- Genome Project: genome project information
- UniGene: gene-oriented clusters of transcript sequences
- CDD: conserved protein domain database
- 3D Domains: domains from Entrez Structure
- UniSTS: markers and mapping data
- PopSet: population study data sets (epidemiology)
- GEO Profiles: expression and molecular abundance profiles
- GEO DataSets: experimental sets of GEO data
- Cancer Chromosomes: cytogenetic databases
- PubChem BioAssay: bioactivity screens of chemical substances
- GENSAT: gene expression atlas of mouse central nervous system
- Probe: sequence-specific reagents
Genbank
The NCBI has had responsibility for making available the GenBank DNA sequence database since 1992. GenBank coordinates with individual laboratories and other sequence databases such as those of the European Molecular Biology Laboratory and the DNA Database of Japan.
Since 1992, NCBI has grown to provide other databases in addition to GenBank. NCBI provides Online Mendelian Inheritance in Man, the Molecular Modeling Database (3D protein structures), the Unique Human Gene Sequence Collection, a Gene Map of the Human genome, a Taxonomy Browser, and coordinates with the National Cancer Institute to provide the Cancer Genome Anatomy Project.
The NCBI has software tools that are available by WWW browsing or by FTP. For example, BLAST is a sequence similarity searching program. BLAST can do sequence comparisons against the GenBank DNA database in less than 15 seconds.
NLM Catalog
The NLM Catalog provides access to NLM bibliographic data for over 1.2 million journals, books, audiovisuals, computer software, electronic resources, and other materials via the NCBI Entrez retrieval system. Updated every weekday, the NLM Catalog is an alternative search interface to the bibliographic records resident in LocatorPlus.
See also
- Chemistry resources
External link
| Databases supported by Bioinformatic Harvester |
| UniProt | SOURCE | SMART | SOSUI | PSORT | HomoloGene | gfp-cdna | IPI | OMIM NCBI-BLAST | Genome-Browser | Ensembl | RZPD | STRING | iHOP | Entrez |
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