G2 phase
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G2 phase is a stage in the cell cycle, and is the final stage of interphase. It follows successful completion of DNA synthesis and chromosomal replication in S phase, and occurs during a period of time - often four to five hours. In this phase, the cell prepares itself for mitosis, or M phase, initiated by prophase.
At the end of this gap is another control checkpoint, the G2 Checkpoint, to determine if the cell can now proceed to enter M mitosis and divide. The G2 checkpoint prevents cells from entering mitosis when DNA was damaged since the last division, providing an opportunity for DNA repair and stopping the proliferation of damaged cells. Because the G2 checkpoint helps to maintain genomic stability, it is an important focus in understanding the molecular causes of cancer.
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