K. Barry Sharpless
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Karl Barry Sharpless (born April 28, 1941) is an American chemist renowned for his work on organometallic chemistry.
In 2001 he won the Nobel Prize in Chemistry for his work on stereoselective oxidation reactions (Sharpless epoxidation, Sharpless bishydroxylation, Sharpless aminohydroxylation). This prize was shared with William S. Knowles and Ryoji Noyori (for their work on stereoselective hydrogenation). Currently he spends much of his time promoting click chemistry which are selective, exothermic reactions which occur under mild conditions in water; the most successful variant of which is the alkyne-azide (3 + 2) cycloaddition to form 1,2,3-triazoles.
Sharpless was born in Philadelphia. He graduated from Friends' Central School in 1959. He continued his studies at Dartmouth College (1963) and earned his Ph.D from Stanford University in 1965. He continued post-doctoral work at Stanford University and Harvard University.
Sharpless has been a professor at the Massachusetts Institute of Technology and Stanford University. He currently holds the W. M. Keck professorship in chemistry at The Scripps Research Institute.
| width="" align="" valign="" style="padding-left:;"| 1901: van 't Hoff
1902: E.Fischer
1903: Arrhenius
1904: Ramsay
1905: von Baeyer
1906: Moissan
1907: Buchner
1908: Rutherford
1909: Ostwald
1910: Wallach
1911: Curie
1912: Grignard, Sabatier
1913: Werner
1914: Richards
1915: Willstätter
1918: Haber
1920: Nernst
1921: Soddy
1922: Aston
1923: Pregl
1925: Zsigmondy
1926: Svedberg
1927: Wieland
1928: Windaus
1929: Harden, von Euler‑Chelpin
1930: H.Fischer
1931: Bosch, Bergius
1932: Langmuir
1934: Urey
1935: F.Joliot‑Curie, I.Joliot‑Curie
1936: Debye
1937: Haworth, Karrer
1938: Kuhn
| width="" align="" valign="" style="padding-left:;"| 1939: Butenandt, Ružička
1943: de Hevesy
1944: Hahn
1945: Virtanen
1946: Sumner, Northrop, Stanley
1947: Robinson
1948: Tiselius
1949: Giauque
1950: Diels, Alder
1951: McMillan, Seaborg
1952: Martin, Synge
1953: Staudinger
1954: Pauling
1955: du Vigneaud
1956: Hinshelwood, Semyonov
1957: Todd
1958: Sanger
1959: Heyrovský
1960: Libby
1961: Calvin
1962: Perutz, Kendrew
1963: Ziegler, Natta
1964: Hodgkin
1965: Woodward
1966: Mulliken
1967: Eigen, Norrish, Porter
1968: Onsager
1969: Barton, Hassel
1970: Leloir
1971: Herzberg
1972: Anfinsen, Moore, Stein
1973: E.O.Fischer, Wilkinson
| width="" align="" valign="" style="padding-left:;"| 1974: Flory
1975: Cornforth, Prelog
1976: Lipscomb
1977: Prigogine
1978: Mitchell
1979: Brown, Wittig
1980: Berg, Gilbert, Sanger
1981: Fukui, Hoffmann
1982: Klug
1983: Taube
1984: Merrifield
1985: Hauptman, Karle
1986: Herschbach, Lee, Polanyi
1987: Cram, Lehn, Pedersen
1988: Deisenhofer, Huber, Michel
1989: Altman, Cech
1990: Corey
1991: Ernst
1992: Marcus
1993: Mullis, Smith
1994: Olah
1995: Crutzen, Molina, Rowland
1996: Curl, Kroto, Smalley
1997: Boyer, Walker, Skou
1998: Kohn, Pople
1999: Zewail
2000: Heeger, MacDiarmid, Shirakawa
2001: Knowles, Noyori, Sharpless
2002: Fenn, Tanaka, Wüthrich
2003: Agre, MacKinnon
2004: Ciechanover, Hershko, Rose
2005: Grubbs, Schrock, Chauvin
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