List of drugs affected by grapefruit
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This page has a list of drugs that are known to be affected by grapefruit. These interactions are generally caused by the fruit's naringin and bergamottin interfering with the enzyme cytochrome P450 isoform CYP3A4 in the liver.
The list is ordered by its most common chemical name, followed by alternate chemical names and various trade names.
This is an incomplete list and should not be used to verify whether a drug is safe
Interacting
The following drugs definitely interact with enzyme P450:- Bupropion, amfebutamone, Wellbutrin (Welbutrin) - [rxlist.com]
- Paroxetine, paroxetine hydrochloride, Paxil, Seroxat, Aropax, Pondera, Deroxat, Cebrilin - [mentalhealth.com]
- Valproate semisodium, divalproex sodium, Depakote, Epival - [stanford.edu]
Probably Non-Interacting
The following drugs, at least when not interacting with other drugs, are probably safe when consumed with grapefruits, or any source of enzyme P450:- Lamotrigine, Lamictal - [stanford.edu]
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