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Mesaconic acid

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Mesaconic acid
Mesaconic acid
Chemical name (2E)-2-methylpent-2-enedioic acid
Chemical formula C6H8O4
Molecular mass 144.12 g/mol
CAS number [498-24-8]
Density 1.31 g/cm3
Melting point 202-204 °C
Boiling point unknown °C
SMILES C/C(=C\CC(=O)O)C(O)=O
[Chemical infoboxDisclaimer and references]

Mesaconic acid, C6H8O4, is one of several isomeric carboxylic acids obtained from citric acid. Is used as a fire retardant, recent studies revealed this acid is a competitive inhibitor of fumarate reduction.

History

This acid was studied for the first time by Dutch chemist Jacobus H. van't Hoff in 1874. Later American biochemist Horace Albert Barker and his team successfully isolated this acid from fermenting bacterium Clostridium tetanomorphum in 1950s. Further studies led him to discover this organic compound was involved in vitamin B12 coenzymes synthesis.

References

External links

 


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