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Nitrogen mustard

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The nitrogen mustards are cytotoxic chemotherapy agents similar to mustard gas. Although their common use is medicinal, in principle these compounds may also be used for chemical warfare purposes.

The prototype nitrogen mustard drug is mustine which is no longer commonly in use but was the first drug to be used as an anticancer chemotherapeutic. It is a schedule 1 substance in the Chemical Weapons Convention. Other nitrogen mustards include cyclophosphamide, chlorambucil, uramustine and melphalan.

Ovation had just bought the rights to nitrogen mustard. Apparently they buy medications that are used by very small percentage of the population. A New York Times article has mentioned that only about 5000 people use therapeutic nitrogen mustard in the United States.

Examples of nitrogen mustards that can be used for chemical warfare purposes and their military weapon designations include:

All belligerent nations stock-piled large amounts of munitions containing nitrogen mustard gas during the Second World War, but none were used in combat. As with all types of mustard gas, nitrogen mustard is a powerful and persistent blister agent.

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This article forms part of the series
Chemical warfare
Blood agents: Cyanogen chloride (CK) – Hydrogen cyanide (AC)
Blister agents: Lewisite (L) – Sulfur mustard gas (HD, H, HT, HL, HQ) – Nitrogen mustard gas (HN1, HN2, HN3)
Nerve agents: G-Agents: Tabun (GA) – Sarin (GB) – Soman (GD) – Cyclosarin (GF) | V-Agents: VEVGVMVX
Pulmonary agents: ChlorineChloropicrin (PS) – Phosgene (CG) – Diphosgene (DP)
Incapacitating agents: Agent 15 (BZ) – KOLOKOL-1
Riot control agents: Pepper spray (OC) – CS gasCN gasCR gas

 


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