Oxymorphone
Encyclopedia : O : OX : OXY : Oxymorphone
Oxymorphone (Numorphan) is a powerful semi-synthetic narcotic analgesic that is derived from morphine, and is approximately 6-8 times more potent. Clinically, it is administered via injection, or suppository; typically in dosages of 1mg (injected) to 5mg (suppository). As a narcotic, oxymorphone can be habit forming, and lead to addiction.
Contents
Chemical Structure:
The chemical structure of Oxymorphone could be also described as 14-Hydroxydihydromorphinone.Usage:
Oxymorphone is typically used for the relief of moderate to severe pain and also as a preoperative medication to alleviate apprehension, maintain anesthesia, and as an obstetric analgesic. Additionally, it can be used for the alleviation of patients with dyspnea associated with acute left ventricular failure and pulmonary edema.Physical characteristics:
Oxymorphone HCL occurs as odorless white crystals or white to off-white powder. It will darken in color with prolonged exposure to light. One gram of oxymorphone is soluble in 4ml of water and it is slightly soluble in alcohol and ether. The commercially available injection has a pH of 2.7-4.5.Drug classification:
Oxymorphone is a schedule II (CII) controlled substance.Toxicity:
Oxymorphone overdosage is characterized by respiratory depression, extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. In a severe case of overdose, apnea, circulatory collapse, cardiac arrest, and death may occur.Brand Name:
NumorphanReferences:
- 1.
External links
- For a full list of external links to MSDSs, spectroscopic data, commercial chemicals suppliers etc. for this compound, see [Chemical sources].
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