Pentachlorophenol
Encyclopedia : P : PE : PEN : Pentachlorophenol
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Pentachlorophenol (C6HCl5O) is a synthetic fungicide which is an organochloride. It is toxic to humans.
Pentachlorophenol has historically been used as a pesticide and wood preservative.
In 1984 (or 1987 — references vary), the purchase and use of pentachlorophenol was restricted in the United States, and the general public may no longer buy it. It still has some industrial use as a wood preservative for utility poles, railroad ties, and wharf pilings.
Exposures to pentachlorophenol measured in minute quantities has been shown to affect the endocrine system of vertebrate life forms and may lead to immune system disfunction, and disruption of normal sexual, cognitive, physical and emotional development. It has also been linked to trans-generational cancer through disruption of foetal development.
Its main action on the cell is to uncouple oxidative phosphorylation and therefore deplete levels of cellular ATP.
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