R-factor
Encyclopedia : R : RF : RFA : R-factor
R-factor is an old name for a
plasmid that codes for
antibiotic resistance. Often, R-factors code for more than one antibiotic resistance factor: genes that encode resistance to unrelated
antibiotics may be carried on a single R-factor. Many R-factors can pass from one bacterium to another through
bacterial conjugation and are a common means by which antibiotic resistance spreads between bacterial species, genera and even families, for example RP1, a plasmid that encodes resistance to
ampicillin,
tetracycline and
kanamycin originated in a species of
Pseudomonas, from the Family
Pseudomonadaceae can also be maintained in bacteria belonging to the family
Enterobacteriaceae, such as
Escherichia coli.
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