Stroke volume
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In cardiovascular physiology, stroke volume (SV) is the volume of blood ejected from a ventricle with each beat of the heart.
Contents
Calculation
Its value is obtained by subtracting end-systolic volume (ESV) from end-diastolic volume (EDV) for a given ventricle:
- [SV = EDV - ESV]
Influence on cardiac output
Stroke volume, along with heart rate (HR), is one of the determinants of cardiac output (CO):
- [CO = SV \times HR]
Determinants
Men, on average, have higher stroke volumes than women due to the larger size of their hearts. However, stroke volume depends on several factors such as heart size, end-diastolic volume, contractility, duration of contraction, preload, and afterload.Exercise
Prolonged aerobic exercise may also increase stroke volume, which frequently results in a slower heart rate. Reduced heart rate prolongs ventricular diastole (filling), increasing end-diastolic volume, and ultimately allowing more blood to be ejected.Preload
Stroke volume is intrinsically controlled by preload (the degree to which the ventricles are stretched prior to contracting). An increase in the volume or speed of venous return will increase preload and, through the Frank-Starling law of the heart, will increase stroke volume. Decreased venous return has the opposite effect, causing a reduction in stroke volume.Afterload
Elevated afterload (commonly measured as the aortic pressure during systole) reduces stroke volume. Though not usually affecting stroke volume in healthy individuals, increased afterload will hinder the ventricles in ejecting blood, causing reduced stroke volume. Increased afterload may be found in aortic stenosis and arterial hypertension.See also
References
External links
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