Succinic acid
Encyclopedia : S : SU : SUC : Succinic acid
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| Other names | succinic acid ethane-1,2-dicarboxylic acid |
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| Density | 3 |
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Succinic acid, originally called spirit of amber, is a dicarboxylic acid with the formula:
- HOOC-CH2-CH2-COOH
This is catalysed by the enzyme succinate dehydrogenase (or complex II of the mitochondrial ETC). The complex is a 4 subunit membrane-bound lipoprotein which couples the oxidation of succinate to the reduction of ubiquinone. Intermediate electron carriers are FAD and three Fe2S2 clusters part of subunit B.
Esters of succinic acid are called dialkyl succinates.
History
Spirit of amber was procured from amber by pulverising and distilling it by a sand heat (a sand bath; vessel filled with heated sand). It was chiefly used externally for rheumatic aches and pains, and internally in inveterate gleets.Safety
The acid is combustible and corrosive, capable of causing burns. "Harmful by inhalation, ingestion and through skin absorption. Wash after handling. Eye contact may cause serious damage."References
- This article incorporates content from the 1728 Cyclopaedia, a publication in the public domain.
See also
- Oil of amber, procured by heating succinic acid
External links
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