Sulfonamide

Encyclopedia : S : SU : SUL : Sulfonamide

The structure of the sulfonamide group

In chemistry, the sulfonamide functional group is -S(=O)₂-NH₂, a sulfone group connected to an amine group.

A sulfonamide (compound) is a compound that contains this group. The general formula is RSO₂NH₂, where R is some organic group. For example, "methanesulfonamide" is CH₃SO₂NH₂. Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group with an amine group.

In medicine, the term "sulfonamide" is sometimes used as a synonym for sulfa drug, a derivative or variation of sulfanilamide.

See also

• Sulfa drug.

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