Thymidine

Encyclopedia : T : TH : THY : Thymidine

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Thymidine (also called deoxythymidine, ribosylthymine, and thymine deoxyriboside) is a chemical compound which is a pyrimidine nucleoside. Thymidine is the DNA base T, which pairs with adenosine in double stranded DNA.

Structure and properties

In its composition, thymidine is deoxyribose (a pentose sugar) joined to the pyrimidine base thymine and is similar to cytidine and the RNA base uridine.

Thymidine can be phosphorylated with one, two or three phosphoric acid groups, creating respectively TMP, TDP or TTP (thymidine mono- di- or triphosphate).

It exists in solid form as small white crystals or white crystalline powder, has a molecular weight of 242.229 u, and has a melting point of 185 °C. The stability of thymidine under standard temperature and pressure (STP) is very high.

Thymidine is non-toxic and is a naturally accuring compound that exists in all living organisms and DNA viruses. 25% of DNA is composed of thymidine. RNA does not have thymidine and has uridine instead.

Modified Analogs of Thymidine

Iododeoxyuridine

External links

• For a full list of external links to MSDSs, spectroscopic data, commercial chemicals suppliers etc. for this compound, see [Chemical sources].

 

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