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Topotecan

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Topotecan (Hycamtin®) is a chemotherapy agent that is a topoisomerase 1 inhibitor. It is used to treat ovarian cancer and lung cancer, as well as other cancer types.

Administration

IV, although oral forms are under investigation.

Side effects

Chemotherapeutic agents (L01) [ edit] - Chemotherapy regimens
L01A - Alkylating agents: Cyclophosphamide | Chlorambucil | Melphalan | Mechlorethamine | Ifosfamide | Busulfan | ThioTEPA | Lomustine | Streptozocin | Temozolomide | Dacarbazine | Cisplatin | Carboplatin | Oxaliplatin | Procarbazine | Uramustine
L01B - Antimetabolites: Methotrexate | Pemetrexed | Fludarabine Cytarabine | Fluorouracil | Floxuridine | Gemcitabine | Capecitabine
L01C - Plant alkaloids: Vinblastine | Vincristine | Vinorelbine | Etoposide | Paclitaxel | Docetaxel
L01D - Cytotoxic/antitumour antibiotics: Anthracycline family (Doxorubicin | Daunorubicin | Epirubicin | Idarubicin | Mitoxantrone) | Bleomycin | Mitomycin | Hydroxyurea
L01X - Other, including Topoisomerase inhibitors: Topotecan | Irinotecan

 


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